The Hippo Signaling Pathway and Cancer
The Hippo signaling pathway is rapidly gaining recognition as an important player in organ size control and tumorigenesis, and many leading scientists are showing increased interest in this growing field and it's relation to cancer. For instance, for the past two years, over 60 researchers from all over the world, have gathered annually for an intensive "Hippo Pathway Workshop" in Rome, Italy. This year, the workshop has been sponsored by Keystone Symposium and will be held in Monterey, California in Spring, 2013.This confirms the growing interest for the Hippo field within the international scientific community. The prospective list of the chapters covers virtually all aspects of tumor biology. This is because members of the Hippo Pathway have been associated with numerous well-established cell signaling pathways, just to name a few; Ras, Wnt, TGFbeta and p53. Moreover, Hippo signaling is not solely involved in regulating "classic" tumor characteristics such as cell proliferation, survival and growth, but is also diversely involved in cell-autonomous and non-cell-autonomous differentiation, migration and organ size control. The primary audience are researchers interested in basic science in the areas of tumor suppression, cell cycle and size regulation, development and differentiation.
- 2013 Springer
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